gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0545 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CANNABINOID RECEPTOR
SUBFAMILY CB1

Cross References:
UniProt P47746 | Q5SF33 EMBL U17985 | U40709 | Y18374 | AY522555 | AY522554 | U22948 | AF153345 | AK139417 | BC070447 | BC079564
InterPro IPR002230 | IPR000810 | IPR000276 GPCRDB CNR1_MOUSE
GENEID 12801
PRINTS PR00522 | PR00362 | PR00237 PFAM PF00001

Details:
NAME CANNABINOID RECEPTOR_CB1_Mus musculus-2
DESCRIPTION Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Cnr1
SEQUENCE
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
FRAGMENT NO

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Scaffold:
TYPE FAN( factor associated with neutral sphingomyelinase activation) REFERENCES 11306675

Coupling with G-proteins:
Family:Gi/o REFERENCES:2165569
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory