gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0570 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CC)
SUBFAMILY CCR4

Cross References:
UniProt P51680 EMBL X90862 | U15208
InterPro IPR000190 | IPR002239 | IPR000355 | IPR000276 GPCRDB CCR4_MOUSE
GENEID 12773
PRINTS PR00635 | PR00657 | PR01109 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CC)_CCR4_Mus musculus
DESCRIPTION C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4)(CD194 antigen).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Ccr4 | Cmkbr4
SEQUENCE
MNATEVTDTTQDETVYNSYYFYESMPKPCTKEGIKAFGEVFLPPLYSLVFLLGLFGNSVV
VLVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIVSWMYLVG
FYSGIFFIMLMSIDRYLAIVHAVFSLKARTLTYGVITSLITWSVAVFASLPGLLFSTCYT
EHNHTYCKTQYSVNSTTWKVLSSLEINVLGLLIPLGIMLFWYSMIIRTLQHCKNEKKNRA
VRMIFGVVVLFLGFWTPYNVVLFLETLVELEVLQDCTLERYLDYAIQATETLGFIHCCLN
PVIYFFLGEKFRKYITQLFRTCRGPLVLCKHCDFLQVYSADMSSSSYTQSTVDHDFRDAL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9169480
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory