gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0571 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CC)
SUBFAMILY CCR4

Cross References:
UniProt P51679 | Q9ULY6 | Q9ULY7 EMBL X85740 | AB023888 | AB023889 | AB023890 | AB023891 | AB023892 | AY322539 | BC069139 | BC071751 | BC074935
InterPro IPR000190 | IPR002239 | IPR000355 | IPR000276 GPCRDB CCR4_HUMAN
GENEID 1233 MIM 604836
PRINTS PR00635 | PR00657 | PR01109 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CC)_CCR4_Homo sapiens
DESCRIPTION C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4)(K5-5) (CD194 antigen).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CCR4 | CMKBR4
SEQUENCE
MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVV
VLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVG
FYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYT
ERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKA
VKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLN
PIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9169480
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory