gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0595 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CC)
SUBFAMILY CCR7

Cross References:
UniProt P32248 EMBL L08176 | L31584 | L31582 | L31583 | L31581 | AY587876 | BC035343
InterPro IPR001718 | IPR000355 | IPR000276 GPCRDB CCR7_HUMAN
GENEID 1236 MIM 600242
PRINTS PR00657 | PR00641 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CC)_CCR7_Homo sapiens
DESCRIPTION C-C chemokine receptor type 7 precursor (C-C CKR-7) (CC-CKR-7) (CCR-7)(MIP-3 beta receptor) (EBV-induced G-protein coupled receptor 1)(EBI1) (BLR2) (CD197 antigen) (CDw197).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CCR7 | CMKBR7 | EBI1 | EVI1
SEQUENCE 
MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWF
LPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAK
SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV
GIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMS
FCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCEL
SKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRH
IRRSSMSVEAETTTTFSP
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9153236
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory