gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0597 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CC)
SUBFAMILY CCR8

Cross References:
UniProt P51685 | Q3KNQ8 EMBL Z79782 | Y08456 | U45983 | AF005210 | U62556 | D49919 | BC069067 | BC074743 | BC107159
InterPro IPR004068 | IPR000355 | IPR000276 GPCRDB CCR8_HUMAN
GENEID 1237 MIM 601834
PRINTS PR00657 | PR01530 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CC)_CCR8_Homo sapiens-1
DESCRIPTION C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (GPR-CY6)(GPRCY6) (Chemokine receptor-like 1) (CKR-L1) (TER1) (CMKBRL2) (CC-chemokine receptor CHEMR1) (CDw198 antigen).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CCR8 | CKRL1 | CMKBR8 | CMKBRL2
SEQUENCE
MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9207005
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory