gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0608 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CX3CR1

Cross References:
UniProt P49238 EMBL U20350 | U28934 | AY016370 | BC028078
InterPro IPR005387 | IPR001277 | IPR000276 GPCRDB CX3C1_HUMAN
GENEID 1524 MIM 601470 | 609423
PRINTS PR00645 | PR01562 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CX3CR1_Homo sapiens
DESCRIPTION CX3C chemokine receptor 1 (C-X3-C CKR-1) (CX3CR1) (Fractalkinereceptor) (G-protein coupled receptor 13) (V28) (Beta chemokinereceptor-like 1) (CMK-BRL-1) (CMKBLR1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CX3CR1 | CMKBRL1 | GPR13
SEQUENCE 
MDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSK
KPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNAMCKFTTAFFFIGFFGSIFFI
TVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVAAPQFMFTKQKENECLGDYP
EVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVF
FLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKF
RRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9390561
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory