gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0618 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR1

Cross References:
UniProt O97571 EMBL AF047047
InterPro IPR001277 | IPR000276 | IPR000174 | IPR000057 GPCRDB CXCR2_CANFA
GENEID 478905
PRINTS PR00645 | PR00237 | PR00427 | PR00573 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR1_Canis familiaris
DESCRIPTION High affinity interleukin-8 receptor B (IL-8R B) (CXCR-2) (GRO/MGSAreceptor) (CD182 antigen).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE IL8RB | CXCR2
SEQUENCE
MEYINWDNYSLEDLFGDIDNYTYNTEMPIIPADSAPCRPESLDINKYAVVVIYVLVFVLN
LLGNSLVIMVVLYSRVSHSVTDVYLLNLAIADLLFALTLPIWAVSKVKGWIFGTPLCKIV
SLLKEVNFYSGILLLASISMDRYLAIVHATRRLTQKKHWVKFICLGIWALSLILSLPIFV
FRRAINPPYSSPVCYEDMGTNTTKLRIVMRALPQTFGFIVPLMIMLFCYGLTLRTLFEAH
MGQKHRAMRVIFAVVLVFLLCWLPYNLVADTLMRLQAIEETCQRRNDIGRALDATEILGF
FHSCLNPLIYAFIGQKFRHGLLKIMAFHGLISKEYLPKDSRPSFVGSSSANTSTTF
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 10973280

Coupling with G-proteins:
Family:Gi/o REFERENCES:9390561
1GPR0223Galpha-i2-Canis familiaris


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory