gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0623 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR1

Cross References:
UniProt P25024 | Q2YEF8 | Q2YEG4 | Q2YEG5 | Q2YEG7 | Q2YEG8 | Q53R18 | Q6IN95 EMBL L19591 | L19592 | M68932 | X65858 | U11870 | AY916762 | AY916763 | AY916764 | AY916765 | AY916766 | AY916769 | AY916772 | AY916773 | CR541994 | CR542029 | AY651785 | AC097483 | BC028221 | BC072397 | AB032728 | AB032729 | AB032730 | AB032731 | AB032732
InterPro IPR001277 | IPR000276 | IPR000174 | IPR001355 PDB 1ILP | 1ILQ GPCRDB CXCR1_HUMAN
GENEID 3577 MIM 146929
PRINTS PR00645 | PR00237 | PR00427 | PR00572 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR1_Homo sapiens
DESCRIPTION High affinity interleukin-8 receptor A (IL-8R A) (IL-8 receptor type1) (CXCR-1) (CD181 antigen) (CDw128a).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE IL8RA | CMKAR1 | CXCR1
SEQUENCE
MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLV
MLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVN
FYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHP
NNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRA
MRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCL
NPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 10973280

Coupling with G-proteins:
Family:Gi/o REFERENCES:9390561
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory