gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0628 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR2

Cross References:
UniProt P35344 EMBL L24445
InterPro IPR001277 | IPR000276 | IPR000174 | IPR000057 GPCRDB CXCR2_RABIT
PRINTS PR00645 | PR00237 | PR00427 | PR00573 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR2_Oryctolagus cuniculus
DESCRIPTION High affinity interleukin-8 receptor B (IL-8R B) (CXCR-2) (GRO/MGSAreceptor) (CD182 antigen).
SPECIES Oryctolagus cuniculus COMMON NAME Rabbit NCBI Taxonomy 9986
GENE IL8RB | CXCR2
SEQUENCE
MQEFTWENYSYEDFFGDFSNYSYSTDLPPTLLDSAPCRSESLETNSYVVLITYILVFLLS
LLGNSLVMLVILYSRSTCSVTDVYLLNLAIADLLFATTLPIWAASKVHGWTFGTPLCKVV
SLVKEVNFYSGILLLACISVDRYLAIVHATRTMIQKRHLVKFICLSMWGVSLILSLPILL
FRNAIFPPNSSPVCYEDMGNSTAKWRMVLRILPQTFGFILPLLVMLFCYVFTLRTLFQAH
MGQKHRAMRVIFAVVLIFLLCWLPYNLVLLTDTLMRTHVIQETCERRNDIDRALDATEIL
GFLHSCLNPIIYAFIGQKFRYGLLKILAAHGLISKEFLAKESRPSFVASSSGNTSTTL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 12888558

Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 10973280

Coupling with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory