gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0659 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOKINE RECEPTOR (CX3C)
SUBFAMILY CXCR4

Cross References:
UniProt Q9MZP1 EMBL AF172222
InterPro IPR000355 | IPR001277 | IPR000276 GPCRDB Q9MZP1_MANLE
PRINTS PR00657 | PR00645 | PR00237 PFAM PF00001

Details:
NAME CHEMOKINE RECEPTOR (CX3C)_CXCR4_Mandrillus leucophaeus
DESCRIPTION Chemokine receptor CXCR4 .
SPECIES Mandrillus leucophaeus COMMON NAME Drill NCBI Taxonomy 9568
GENE CXCR4
SEQUENCE
IYTSDNYTEEMGSGDYDSIKEPCFREENAHFNRIFLPTIYSIIFLTGIVGNGLVILVMGY
QKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVL
ILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWIPALLLTIPDFIFASVSEADDRFI
CDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYWIIISKLSHSKGHQKRKALKTTVILI
LAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFL
GAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12433920 | 12089144

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory