gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0714 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY C5A

Cross References:
UniProt P30993 EMBL S46665 | S50577
InterPro IPR002234 | IPR001274 | IPR000276 GPCRDB C5AR_MOUSE
PRINTS PR01104 | PR00426 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Mus musculus
DESCRIPTION C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE C5ar1 | C5ar | C5r1
SEQUENCE 
MNSSFEINYDHYGTMDPNIPADGIHLPKRQPGDVAALIIYSVVFLVGVPGNALVVWVTAF
EPDGPSNAIWFLNLAVADLLSCLAMPVLFTTVLNHNYWYFDATACIVLPSLILLNMYASI
LLLATISADRFLLVFKPIWCQKVRGTGLAWMACGVAWVLALLLTIPSFVYREAYKDFYSE
HTVCGINYGGGSFPKEKAVAILRLMVGFVLPLLTLNICYTFLLLRTWSRKATRSTKTLKV
VMAVVICFFIFWLPYQVTGVMIAWLPPSSPTLKRVEKLNSLCVSLAYINCCVNPIIYVMA
GQGFHGRLLRSLPSIIRNALSEDSVGRDSKTFTPSTDDTSPRKSQAV
 FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12835318

Coupling with G-proteins:
Family:Gq/11 REFERENCES:7870028
1GPR0044Galpha-15-Mus musculus
Family:Gi/o REFERENCES:7887933
2GPR0021Galpha-o1-Mus musculus
3GPR0227Galpha-i2-Mus musculus-2
4GPR0289Galpha-i1-Mus musculus
5GPR0331Galpha-i2-Mus musculus-1
6GPR0385Galpha-i3-Mus musculus
7GPR0129Galpha-z-Mus musculus

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