gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0716 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY C5A

Cross References:
UniProt P30992 EMBL X65860
InterPro IPR002234 | IPR001274 | IPR000276 GPCRDB C5AR_CANFA
GENEID 442974
PRINTS PR01104 | PR00426 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Canis familiaris
DESCRIPTION C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE C5AR1 | C5R1
SEQUENCE
MASMNFSPPEYPDYGTATLDPNIFVDESLNTPKLSVPDMIALVIFVMVFLVGVPGNFLVV
WVTGFEVRRTINAIWFLNLAVADLLSCLALPILFSSIVQQGYWPFGNAACRILPSLILLN
MYASILLLTTISADRFVLVFNPIWCQNYRGPQLAWAACSVAWAVALLLTVPSFIFRGVHT
EYFPFWMTCGVDYSGVGVLVERGVAILRLLMGFLGPLVILSICYTFLLIRTWSRKATRST
KTLKVVVAVVVSFFVLWLPYQVTGMMMALFYKHSESFRRVSRLDSLCVAVAYINCCINPI
IYVLAAQGFHSRFLKSLPARLRQVLAEESVGRDSKSITLSTVDTPAQKSQGV
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12835318

Coupling with G-proteins:
Family:Gi/o REFERENCES:7887933
1GPR0223Galpha-i2-Canis familiaris


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory