gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0080 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-2B

Cross References:
UniProt Q8UUG8 | Q8UUP7 | Q8UUP8 | Q8UUP9 | Q8UUQ0 | Q8UUQ1 EMBL AJ315179 | AJ315180 | AJ315181 | AJ315182 | AJ315183 | AJ320211 | AJ320212
InterPro IPR000482 | IPR002231 | IPR000276 GPCRDB 5HT2B_TETFL
PRINTS PR00651 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2B_Tetraodon fluviatilis-1
DESCRIPTION 5-hydroxytryptamine receptor 2B (5-HT-2B) (Serotonin receptor 2B).
SPECIES Tetraodon fluviatilis COMMON NAME Puffer fish NCBI Taxonomy 47145
GENE htr2b
SEQUENCE
MFQAAVGPLQTNISLPEETPGLELNWAALLIVMVIIPTIGGNILVILAVWLEKKLQNATN
FFLMSLAVADLLVGLLVMPIALITILYDSDWPLPEPLCPIWLFLDVLFSTASIMHLCAIS
LDRYIAIKKPIQHSQYKSRAKVMLKIALVWLISICIAIPIPIKGLRNYPHPNNITFTSNH
TCVLKTDTFQEFIIFGSLVAFFIPLTIMMIIYFLTVRVLRKKVYLLRSKVTQRFSYPIIS
TVFQREQAANPPQPEQPDSTGNSLARIQEKTDTDGMSSPTGDEKSFRRLSTMGKKSMQTL
TNEQRASKVLGIVFLLFVVMWCPFFITNITSALCGPCDANIIGRLMEIFSWVGYVSSGIN
PLVYTLFNKTFRQAFTRYITCNYRNFASKEQGRSFRASTVDRMLTHISPRSSVAENAKLF
TKQEIKNETTDYRSPLGCLQPSAQTSTGVVLDKILLTHTENCKQEERVSCV
FRAGMENT NO

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Scaffold:
TYPE MUPP1( multiple activated protein kinase 1) REFERENCES 11150294
TYPE nNOS( neuronal nitric oxide synthase) NOS1 REFERENCES 10734074

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory