gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0866 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY LSH RECEPTOR

Cross References:
UniProt Q98T85 EMBL AF285181
InterPro IPR000276 | IPR002131 | IPR001611 | IPR000307 | IPR002274 GPCRDB Q98T85_ICTPU
PRINTS PR00373 | PR00237 | PR01145 PFAM PF00001 | PF00560

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Ictalurus punctatus
DESCRIPTION Luteinizing hormone receptor precursor.
SPECIES Ictalurus punctatus COMMON NAME Channel catfish NCBI Taxonomy 7998
GENE -
SEQUENCE
MVSRCSVAALLLAVVMRLSRGGAFTCPPICSCTADTLSCTAQTERRTRVPSSTTSTNLRL
AHLPLKEVQSGTFRGLINVSRIEISQSDSIRKIKGEAFLSIHNVIEISILNIIHLSAMEK
GAFTDLPRLRYLSICNTGIRHFPDFSRISSLGLEFFLDMGDNIQLNNIPANAFQGISKAD
MYMNLVRNGFTQIESHAFNGTRLEKLIMKDNWHLIKIHDDAFEGAEGPTLLDVSSTALKS
LPTRGLRGVKVLIARSTPSLKTLPPLDNLAELQEADLTYPSHCCAFHTWKRNNRETAVFD
RFKNLTMLCNMDDQANNMDPSGDDLNDINFHYPDLELCASSSSFKCTPEPDAFNPCEDLL
GHTFLRAITWIVTVFALVGNLAVLLVLLLSHQKLSVSRFLMCNLAFADLCMGFYLLLIAV
ADYRSRQEYYNHATDWQTGMGCGVAGFLTVFASELSIYTLTMITLERWHTITHAMQMSRR
LRLRHMVTMMAIGWGFSFVIALLPVVGVSSYSKVSICLPMDIETPVSQGYVVAVLVINVA
AFLMVCSSYAGIYLSVRNPNVPTRHGHTRMAKRMAVLIFTDFLCMAPISFFAISAALHMP
LISVSQSKILLILFYPINSLCNPFLYTIFTRAFRRDMCLLLSRCGCCHAQAEFYRSQGLL
GFTLAPRKKRVRKPHSKNFRAYHVKLQGCIFNKAAT
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11108263

Scaffold:
TYPE GIPC( GAIP-interacting protein) REFERENCES 14507927
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 14507927
TYPE p38JAB1 REFERENCES 10788448

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory