gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0869 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY LSH RECEPTOR

Cross References:
UniProt O46387 EMBL AF029295
InterPro IPR000276 | IPR002131 GPCRDB O46387_MUSVI
PRINTS PR00373 | PR00237 PFAM PF00001

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Mustela vison
DESCRIPTION Luteinizing hormone receptor .
SPECIES Mustela vison COMMON NAME American mink NCBI Taxonomy 452646
GENE LHr
SEQUENCE
FLRVLIWLINILAIMGNVTVLFVLLTSRYKMTVPRFLMCNLSFADFCMGFYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSAAGFFTVFSSELSVYTLTVITLERWHTITYALQLDQKLRL
RHAILIMLGGWLFSTLIATLPLVGVSNYMKVSICLPMDVETTLSQVYILTILILNVVAFT
IICACYIKIYFAVQNPELMANNKDTKIAKKMAVLIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPVNSCANPFLYAIFTKAFQRDFFLLLSKFGCCKRRVELYRRKDFVAYT
SNCKNGFTGSNKPSQSTLKLSPLQCQYTTVPDKTC
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11108263

Scaffold:
TYPE GIPC( GAIP-interacting protein) REFERENCES 14507927
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 14507927
TYPE p38JAB1 REFERENCES 10788448

Coupling with G-proteins:
No information


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athina University of Athens
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Biophysics
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Laboratory