gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0873 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY LSH RECEPTOR

Cross References:
UniProt O42500 EMBL U92082
InterPro IPR000276 | IPR002131 | IPR002273 GPCRDB O42500_MELGA
PRINTS PR00373 | PR00237 | PR01144 PFAM PF00001

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Meleagris gallopavo
DESCRIPTION Luteinizing hormone receptor .
SPECIES Meleagris gallopavo COMMON NAME Common turkey NCBI Taxonomy 9103
GENE -
SEQUENCE
LILNTKNLLHIEDGAFRNLPRLKYLSICNTGIIEFPDLTQIFSSEAHFILELCDNLHMTT
IPQNAFQGMSNESLTLKLYKNGFEDIHSHAFNGTKLNQLILKDNKNLRRIHNDALRGATG
PDVLDISSTALESLPSYGLEAIQVLNAESSYSLKRLPPLDKFSSLLEAVLTYPSHCCAFR
NLRTEKQNSMLSIFDNFSKRCESIVRKTTSEIFYRDASFNTSLGQRKSTRTHLEQPKILT
CTPEPDAFNPCEDILGYSFLRVLIWFINILAIAGNLIVLLVLITSHYKLMVPRFLMCNLS
FADFCMGLYLVLIASVDAQTSGQYYNHAIYWQTGSGCSTAGFFTVFASELSVYTLTVITI
ERWHTITYAMQLDRQLRLRHAVLIMLGGWVFSILIAVLPLLGVSSYMKVSICLPMDIETG
LSQAYILLILVLNAVAFVVICACYIKIYIAVQNPELVAANKDTKIAKRMAILIFTDFTCM
APISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFFLLMSKLG
CCKSRAELCRMNYFSAYTSNCKNGSSAPGPSKASQALLLLSASEKLCKTRRSTKKSQPEC
Q
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11108263

Scaffold:
TYPE GIPC( GAIP-interacting protein) REFERENCES 14507927
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 14507927
TYPE p38JAB1 REFERENCES 10788448

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1516719
1GPR0030Galpha-11-Meleagris gallopavo


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory