gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0893 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY TSH RECEPTOR

Cross References:
UniProt Q9BGN4 EMBL AF218264
InterPro IPR000276 | IPR002131 | IPR002274 GPCRDB TSHR_FELCA
GENEID 493842
PRINTS PR00373 | PR00237 | PR01145 PFAM PF00001

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Felis silvestris catus
DESCRIPTION Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor).
SPECIES Felis silvestris catus COMMON NAME Cat NCBI Taxonomy 9685
GENE TSHR
SEQUENCE
MRQTPLLQLALLLSLPRSLGGKGCPSPPCECHQEDDFRVTCKDIHRIPSLPPSTQTLKFI
ETHLKTIPSRAFSNLPNISRIYLSIDATLQRLESHSFYNLSKMTHIEIRNTRSLTYIDPG
ALKELPLLKFLGIFNTGLGVFPDLTKVYSTDVFFILEITDNPYMTSIPANAFQGLCNETL
TLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLTAIDQDAFGGVYSGPTLLDVSYTSVTA
LPSKGLEHLKELIARNTWTLKKLPLTLSFLHLTRADLSYPSHCCAFKNQKKIRGILESFM
CNDSSIRSLRQRKSVNALNGPFDQEYEEYLGDSHAGYKDNSKFQDTRSNSHYYVFFEEQD
EILGFGQELKNPQEETLQAFDSHYDYTVCGGNEDMVCTPKSDEFNPCEDIMGYKFLRIVV
WFVSLLALLGNVFVLIILLTSHYKLTVPRFLMCNLAFADFCMGMYLLLIASVDLYTHSEY
YNHAIDWQTGPGCNAAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKMRLRHAYAI
MVGGWVCCFLLALLPLVGISSYAKVSICLPMDTETPLALAYIILVLLLNIVAFIIVCSCY
VKIYITVRNPQYNTGDKDTKIAKRMAVLIFTDFMCMAPISFYALSALMNKPLITVTNSKI
LLVLFYPLNSCANPFLYAIFTKTFQRDVFILLSKFGICKRQAQAYRGQRVSPKNSTGIQV
QKVTRNMRQSLPNMQDDYELLENSHLTPNKQSHISKEYNQTVL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12223484

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory