gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0901 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GONADOTROPIN-RELEASING HORMONE RECEPTOR
SUBFAMILY GNRH1

Cross References:
UniProt P32236 EMBL U00934 | AF034950
InterPro IPR015693 | IPR000276 | IPR001658 GPCRDB GNRHR_BOVIN
GENEID 281798
PRINTS PR00529 | PR00237 PFAM PF00001

Details:
NAME GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH1_Bos taurus
DESCRIPTION Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE GNRHR
SEQUENCE
MANSDSPEQNENHCSAINSSIPLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKL
QNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGM
IHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICNAKIIFTLTR
VLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRV
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11278883
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11035030 | 11328852

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1333190
1GPR0027Galpha-11-Bos taurus


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athina University of Athens
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