gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0904 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GONADOTROPIN-RELEASING HORMONE RECEPTOR
SUBFAMILY GNRH1

Cross References:
UniProt P32237 EMBL L22215 | X72088 | L42937 | L43842 | L43841
InterPro IPR015693 | IPR000276 | IPR001658 GPCRDB GNRHR_SHEEP
GENEID 443413
PRINTS PR00529 | PR00237 PFAM PF00001

Details:
NAME GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH1_Ovis aries
DESCRIPTION Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).
SPECIES Ovis aries COMMON NAME Sheep NCBI Taxonomy 9940
GENE GNRHR
SEQUENCE
MANGDSPDQNENHCSAINSSILLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKL
QNWTQRKEKRKKLSKMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGM
IHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMLICNAKIIFTLTR
VLHQDPHKLQLNQSKNNIPQARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRV
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11278883
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11035030 | 11328852

Coupling with G-proteins:
No information


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athina University of Athens
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Biophysics
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Laboratory