gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0912 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GONADOTROPIN-RELEASING HORMONE RECEPTOR
SUBFAMILY GNRH2

Cross References:
UniProt Q95JG1 EMBL AF353987
InterPro IPR000276 | IPR001658 GPCRDB GNRR2_MACMU
GENEID 574163
PRINTS PR00529 | PR00237 PFAM PF00001

Details:
NAME GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH2_Macaca mulatta
DESCRIPTION Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R).
SPECIES Macaca mulatta COMMON NAME Rhesus macaque NCBI Taxonomy 9544
GENE GNRHR2
SEQUENCE
MSAGNGTPWGSAAGEESWAASGVAVEGSELPTFSAAAKVRVGVTIVLFVSSAGGNLAVLW
SVTRPQPSQLRPSPVRTLFAHLAAADLLVTFVVMPLDATWNITVQWLAEDIACRTLMFLK
LMAMYSAAFLPVVIGLDRQAAVLNPLGSRSGVRKLLGAAWGLSFLLALPQLFLFHTVHRA
GPVPFTQCVTKGSFKARWQETTYNLFTFRCLFLLPLTAMAICYSHIVLSVSSPQTRKGSH
APAGEFALCRSFDNCPRVRLWALRLALLILLTFILCWTPYYLLGLWYWFSPTMLTEVPPS
LSHILFLFGLLNAPLDPLLYGAFTLGCQRGHQELSIDSSNEGSGRMLQQEIHALRQQEVQ
KTVTSRSAGETKDISITSI
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11278883
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11035030 | 11328852

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1333190
1GPR0352Galpha-11-Macaca mulatta


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory