gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0981 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY HISTAMINE RECEPTOR
SUBFAMILY H3

Cross References:
UniProt Q9Y5N1 | Q4QRI7 | Q9GZX2 | Q9H4K8 EMBL AF140538 | AB045369 | AB019000 | AJ296652 | AJ278250 | AF363791 | AL078633 | BC096840
InterPro IPR000276 | IPR003980 GPCRDB HRH3_HUMAN
GENEID 11255 MIM 604525
PRINTS PR00237 | PR01471 PFAM PF00001

Details:
NAME HISTAMINE RECEPTOR_H3_Homo sapiens
DESCRIPTION Histamine H3 receptor (HH3R) (G-protein coupled receptor 97).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE HRH3 | GPCR97
SEQUENCE
MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10347254
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory