gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::G-protein View
Entry 1 of 1 :: GPR0246 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-t
TYPE Galpha-t1

Cross References:
UniProt Q28300 EMBL Z69597 | U65376 | AJ506760
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 403613
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-t1-Canis familiaris
DESCRIPTION Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducinalpha-1 chain).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
POST TRANSLATION MODIFICATIONS null GENE GNAT1
SEQUENCE
MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE
ECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMS
DIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI
IETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH
ESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGNYIK
VQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0475Phosphodiesterase-6-Canis familiaris-1Stimulation15251227 | 15988071 | 14699118
2EFF0476Phosphodiesterase-6-Canis familiaris-2Stimulation15251227 | 15988071 | 14699118
3EFF0477Phosphodiesterase-6-Canis familiaris-3Stimulation15251227 | 15988071 | 14699118
4EFF0478Phosphodiesterase-6-Canis familiaris-4Stimulation15251227 | 15988071 | 14699118
5EFF0479Phosphodiesterase-6-Canis familiaris-5Stimulation15251227 | 15988071 | 14699118
6EFF0480Phosphodiesterase-6-Canis familiaris-6Stimulation15251227 | 15988071 | 14699118

Coupling with GPCRs:
1GPCR2098OPSIN/RHODOPSIN FAMILY_Red-sensitive opsin _Canis familiaris3867351
2GPCR2134OPSIN/RHODOPSIN FAMILY_Rhodopsin_Canis familiaris3867351




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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory