Photo Dr. Margarita Theodoropoulou

Post-doc
mtheodobiol.uoa.gr

EDUCATION
2009 - 2014: Faculty of Biology, University of Athens, PhD in Bioinformatics, entitled "Computational studies in G-protein coupled receptors (GPCRs)".
(Supervisor: Prof. S.J. Hamodrakas)

2008 - 2010: MSc in Bioinformatics, Faculty of Biology, University of Athens

2002 - 2008: BSc in Biology, Faculty of Biology, University of Athens


RESEARCH INTERESTS
1. Membrane proteins.
2. Protein-protein interactions/Biological networks.
3. Signal transduction.
4. Biological Databases.

PUBLICATIONS Search in
Tsaousis, G.N., Theodoropoulou, M.C., Hamodrakas, S.J., Bagos, P.G. (2017) Predicting Alpha Helical Transmembrane Proteins Using HMMs. Methods Mol. Biol. 1552:63-82 [Abstract] [Full Text] doi:10.1007/978-1-4939-6753-7_5.
Baltoumas, F.A., Theodoropoulou, M.C., Hamodrakas, S.J. (2016) Molecular dynamics simulations and structure-based network analysis reveal structural and functional aspects of G-protein coupled receptor dimer interactions. J. Comput. Aided. Mol. Des. Jun;30(6):489-512. [Abstract] [PDF] doi: 10.1007/s10822-016-9919-y.
Kostiou V.D., Theodoropoulou M.C., Hamodrakas S.J. (2016) GprotPRED: Annotation of Galpha, Gbeta and Ggamma subunits of G-proteins using profile hidden Markov models (pHMMs) and application to proteomes.Biochim. Biophys. Acta Volume 1864, Issue 5, pp. 435440 [Abstract] [PDF]doi: 10.1016/j.bbapap.2016.02.005.
Ioannidou, Z.S., Theodoropoulou, M.C., Papandreou, N.C., Willis, J.H., Hamodrakas, S.J. (2014) CutProtFam-Pred: Detection and classification of putative structural cuticular proteins from sequence alone, based on profile Hidden Markov Models. Insect. Biochem. Mol. Biol., Volume 52, September 2014, Pages 51-59. [Abstract] [Full Text] doi: 10.1016/j.ibmb.2014.06.004
Baltoumas, F.A., Theodoropoulou, M.C., Hamodrakas, S.J. (2013) Interactions of the alpha-subunits of heterotrimeric G-proteins with GPCRs, effectors and RGS proteins: A critical review and analysis of interacting surfaces, conformational shifts, structural diversity and electrostatic potentials. Journal of Structural Biology, 182 (2013) 209218. [Abstract] [PDF][Supplement]

Satagopam, V.P., Theodoropoulou, M.C., Stampolakis, C.K., Pavlopoulos, G.A., Papandreou, N.C., Bagos, P.G., Schneider, R., Hamodrakas, S.J. (2010) GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques. Database (Oxford), 2010. [Abstract] [PDF]

Theodoropoulou, M.C., Bagos, P.G., Spyropoulos, I.C., Hamodrakas, S.J. (2008) gpDB: a database of GPCRs, G-proteins, effectors and their interactions. Bioinformatics, 24(12):1471-2[Abstract] [PDF]