gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF1143 ::
FAMILY Tubulins
SUBFAMILY Tubulins
TYPE Tubulin

Cross References:
UniProt Q5SQY0 EMBL AL713922 | CH471072
InterPro IPR002453 | IPR000158 | IPR008280 | IPR000217 | IPR003008
PRINTS PR01163 | PR00423 | PR01161 PFAM PF00091 | PF03953

Details:
NAME Tubulin-Homo sapiens-25
DESCRIPTION Novel protein similar to beta-tubulin 4Q (TUBB4Q) (LOC253936)(Tubulin, beta 8, isoform CRA_c).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RP11-631M21.2 | TUBB8
SEQUENCE 
MNMPSTPLAPTTGTATCSWSASTCTTTRPAVRPPSFPHRPPGNAALPSLMPSRPTQVAGQ
CGAGNNWAKGHYTEGAELMESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSK
IREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSKT
LKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT
SRGSQQYRALTVAEL
 FRAGMENT NO
FUNCTION Tubulin is the major constituent of microtubules
Interacting with G-proteins:
Family:Gi/o REFERENCES:10224115 | 15251227 | 16380086
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
6GPR0020Galpha-o1-Homo sapiens
7GPR0334Galpha-o-Homo sapiens
Family:Gq/11 REFERENCES:16182515
8GPR0002Galpha-q-Homo sapiens-2
9GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:10224115 | 15251227 | 16380086
10GPR0119Galpha-s-Homo sapiens-2
11GPR0263Galpha-s-Homo sapiens-4
12GPR0266Galpha-s-Homo sapiens-5
13GPR0267Galpha-s-Homo sapiens-6
14GPR0277Galpha-s-Homo sapiens-7
15GPR0278Galpha-s-Homo sapiens
16GPR0395Galpha-s-Homo sapiens-3
Family:Gbeta REFERENCES:15251227 | 14671004 | 12807915 | 17705289 | 16380086
17GPR0147Gbeta-1-Homo sapiens
18GPR0155Gbeta-2-Homo sapiens
19GPR0160Gbeta-3-Homo sapiens-1
20GPR0164Gbeta-4-Homo sapiens
21GPR0167Gbeta-5-Homo sapiens-2
22GPR0363Gbeta-3-Homo sapiens-2
23GPR0366Gbeta-5-Homo sapiens-1
24GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 14671004 | 12807915 | 17705289 | 16380086
25GPR0176Ggamma-t1-Homo sapiens
26GPR0179Ggamma-2-Homo sapiens
27GPR0183Ggamma-3-Homo sapiens
28GPR0185Ggamma-4-Homo sapiens
29GPR0188Ggamma-5-Homo sapiens-2
30GPR0192Ggamma-7-Homo sapiens
31GPR0195Ggamma-8-Homo sapiens-2
32GPR0198Ggamma-10-Homo sapiens-2
33GPR0199Ggamma-11-Homo sapiens
34GPR0203Ggamma-12-Homo sapiens
35GPR0205Ggamma-13-Homo sapiens
36GPR0210Ggamma-8-Homo sapiens-1
37GPR0253Ggamma-5-Homo sapiens-1
38GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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Laboratory