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gpDB::G-protein View
Entry 1 of 1 :: GPR0266 ::
CLASS Galpha
FAMILY Gs
SUBFAMILY Galpha-s
TYPE Galpha-s

Cross References:
UniProt O75632 EMBL AF088184
InterPro IPR001019 | IPR000367
PRINTS PR00443 PFAM PF00503

Details:
NAME Galpha-s-Homo sapiens-5
DESCRIPTION Guanine nucleotide-binding protein Gs alpha subunit isoform L2.
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
POST TRANSLATION MODIFICATIONS null GENE -
SEQUENCE 
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKYFIRDEFLRISTASGDGRHYCYPHFT
CAVDTENIRRVFNDCRDIIQRMHLRQYELL
 FRAGMENT NO
FUNCTION -
Effectors:
1EFF0002Adenylate cyclase-1-Homo sapiens-1Stimulation15251227 | 15922020 | 14993377 | 11376933
2EFF0003Adenylate cyclase-1-Homo sapiens-2Stimulation15251227 | 15922020 | 14993377 | 11376933
3EFF0006Adenylate cyclase-2-Homo sapiens-1Stimulation15251227 | 15922020 | 14993377 | 11376933
4EFF0007Adenylate cyclase-2-Homo sapiens-2Stimulation15251227 | 15922020 | 14993377 | 11376933
5EFF0013Adenylate cyclase-3-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
6EFF0020Adenylate cyclase-4-Homo sapiens-1Stimulation15251227 | 15922020 | 14993377 | 11376933
7EFF0021Adenylate cyclase-4-Homo sapiens-2Stimulation15251227 | 15922020 | 14993377 | 11376933
8EFF0030Adenylate cyclase-5-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
9EFF0039Adenylate cyclase-6-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
10EFF0045Adenylate cyclase-7-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
11EFF0055Adenylate cyclase-8-Homo sapiens-1Stimulation15251227 | 15922020 | 14993377 | 11376933
12EFF0056Adenylate cyclase-8-Homo sapiens-2Stimulation15251227 | 15922020 | 14993377 | 11376933
13EFF0062Adenylate cyclase-9-Homo sapiensStimulation15251227 | 15922020 | 14993377 | 11376933
14EFF0705RGS PX1-Homo sapiensStimulation15251227
15EFF0852Src tyrosine kinase-Homo sapiens-1Stimulation11007482 | 15251227 | 12209124
16EFF0853Src tyrosine kinase-Homo sapiens-2Stimulation11007482 | 15251227 | 12209124
17EFF0854Src tyrosine kinase-Homo sapiens-3Stimulation11007482 | 15251227 | 12209124
18EFF0856Src tyrosine kinase-Homo sapiens-5Stimulation11007482 | 15251227 | 12209124
19EFF0857Src tyrosine kinase-Homo sapiens-4Stimulation11007482 | 15251227 | 12209124
20EFF1126Tubulin-Homo sapiens-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
21EFF1127Tubulin-Homo sapiens-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
22EFF1128Tubulin-Homo sapiens-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
23EFF1129Tubulin-Homo sapiens-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
24EFF1130Tubulin-Homo sapiens-13Stimulation of GTPase activity10224115 | 15251227 | 16380086
25EFF1131Tubulin-Homo sapiens-14Stimulation of GTPase activity10224115 | 15251227 | 16380086
26EFF1132Tubulin-Homo sapiens-15Stimulation of GTPase activity10224115 | 15251227 | 16380086
27EFF1133Tubulin-Homo sapiens-16Stimulation of GTPase activity10224115 | 15251227 | 16380086
28EFF1134Tubulin-Homo sapiens-17Stimulation of GTPase activity10224115 | 15251227 | 16380086
29EFF1135Tubulin-Homo sapiens-18Stimulation of GTPase activity10224115 | 15251227 | 16380086
30EFF1136Tubulin-Homo sapiens-19Stimulation of GTPase activity10224115 | 15251227 | 16380086
31EFF1137Tubulin-Homo sapiens-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
32EFF1138Tubulin-Homo sapiens-20Stimulation of GTPase activity10224115 | 15251227 | 16380086
33EFF1139Tubulin-Homo sapiens-21Stimulation of GTPase activity10224115 | 15251227 | 16380086
34EFF1140Tubulin-Homo sapiens-22Stimulation of GTPase activity10224115 | 15251227 | 16380086
35EFF1141Tubulin-Homo sapiens-23Stimulation of GTPase activity10224115 | 15251227 | 16380086
36EFF1143Tubulin-Homo sapiens-25Stimulation of GTPase activity10224115 | 15251227 | 16380086
37EFF1144Tubulin-Homo sapiens-26Stimulation of GTPase activity10224115 | 15251227 | 16380086
38EFF1145Tubulin-Homo sapiens-27Stimulation of GTPase activity10224115 | 15251227 | 16380086
39EFF1146Tubulin-Homo sapiens-28Stimulation of GTPase activity10224115 | 15251227 | 16380086
40EFF1148Tubulin-Homo sapiens-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
41EFF1149Tubulin-Homo sapiens-30Stimulation of GTPase activity10224115 | 15251227 | 16380086
42EFF1150Tubulin-Homo sapiens-31Stimulation of GTPase activity10224115 | 15251227 | 16380086
43EFF1151Tubulin-Homo sapiens-32Stimulation of GTPase activity10224115 | 15251227 | 16380086
44EFF1152Tubulin-Homo sapiens-33Stimulation of GTPase activity10224115 | 15251227 | 16380086
45EFF1153Tubulin-Homo sapiens-34Stimulation of GTPase activity10224115 | 15251227 | 16380086
46EFF1154Tubulin-Homo sapiens-35Stimulation of GTPase activity10224115 | 15251227 | 16380086
47EFF1156Tubulin-Homo sapiens-37Stimulation of GTPase activity10224115 | 15251227 | 16380086
48EFF1157Tubulin-Homo sapiens-38Stimulation of GTPase activity10224115 | 15251227 | 16380086
49EFF1158Tubulin-Homo sapiens-39Stimulation of GTPase activity10224115 | 15251227 | 16380086
50EFF1159Tubulin-Homo sapiens-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
51EFF1160Tubulin-Homo sapiens-40Stimulation of GTPase activity10224115 | 15251227 | 16380086
52EFF1162Tubulin-Homo sapiens-42Stimulation of GTPase activity10224115 | 15251227 | 16380086
53EFF1163Tubulin-Homo sapiens-43Stimulation of GTPase activity10224115 | 15251227 | 16380086
54EFF1164Tubulin-Homo sapiens-44Stimulation of GTPase activity10224115 | 15251227 | 16380086
55EFF1165Tubulin-Homo sapiens-45Stimulation of GTPase activity10224115 | 15251227 | 16380086
56EFF1166Tubulin-Homo sapiens-46Stimulation of GTPase activity10224115 | 15251227 | 16380086
57EFF1167Tubulin-Homo sapiens-47Stimulation of GTPase activity10224115 | 15251227 | 16380086
58EFF1168Tubulin-Homo sapiens-48Stimulation of GTPase activity10224115 | 15251227 | 16380086
59EFF1169Tubulin-Homo sapiens-49Stimulation of GTPase activity10224115 | 15251227 | 16380086
60EFF1170Tubulin-Homo sapiens-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
61EFF1171Tubulin-Homo sapiens-50Stimulation of GTPase activity10224115 | 15251227 | 16380086
62EFF1173Tubulin-Homo sapiens-52Stimulation of GTPase activity10224115 | 15251227 | 16380086
63EFF1174Tubulin-Homo sapiens-51Stimulation of GTPase activity10224115 | 15251227 | 16380086
64EFF1175Tubulin-Homo sapiens-41Stimulation of GTPase activity10224115 | 15251227 | 16380086
65EFF1176Tubulin-Homo sapiens-36Stimulation of GTPase activity10224115 | 15251227 | 16380086
66EFF1177Tubulin-Homo sapiens-29Stimulation of GTPase activity10224115 | 15251227 | 16380086
67EFF1178Tubulin-Homo sapiens-24Stimulation of GTPase activity10224115 | 15251227 | 16380086
68EFF1179Tubulin-Homo sapiens-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
69EFF1180Tubulin-Homo sapiens-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
70EFF1181Tubulin-Homo sapiens-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
71EFF1182Tubulin-Homo sapiens-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR00895-HYDROXYTRYPTAMINE RECEPTOR_5-HT-4_Homo sapiens2849052
2GPCR01015-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Homo sapiens8522988
3GPCR01045-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Homo sapiens8397408
4GPCR0182ADENOSINE RECEPTOR_A2A_Homo sapiens-21662665
5GPCR0185ADENOSINE RECEPTOR_A2A_Homo sapiens-11662665
6GPCR0232ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Homo sapiens8662784
7GPCR0189ADENOSINE RECEPTOR_A2B_Homo sapiens11048721
8GPCR2572CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_ADRENOMEDULIN RECEPTOR_Homo sapiens8549809
9GPCR0304ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Homo sapiens2825170
10GPCR0321ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Homo sapiens-13041227
11GPCR0384ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Homo sapiens-23041227
12GPCR0394ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Homo sapiens2570461
13GPCR2577CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Homo sapiens1331173
14GPCR0737CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Homo sapiens8503909
15GPCR2580CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Homo sapiens2542467
16GPCR2586CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Homo sapiens1280419
17GPCR2592CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Homo sapiens8536644
18GPCR0755DOPAMINE RECEPTOR_D1_Homo sapiens2144334
19GPCR0807DOPAMINE RECEPTOR_D5_Homo sapiens1831904
20GPCR2417PROSTANOID RECEPTOR_DP_Homo sapiens7512962
21GPCR2425PROSTANOID RECEPTOR_EP2_Homo sapiens7910583
22GPCR2432PROSTANOID RECEPTOR_EP3_Homo sapiens11095474
23GPCR2436PROSTANOID RECEPTOR_EP4_Homo sapiens8016385
24GPCR0814ENDOTHELIN RECEPTOR_ET-A_Homo sapiens1849646
25GPCR0846GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Homo sapiens9139796
26GPCR2593GASTRIC INHIBITORY POLYPEPTIDE (GIP) RECEPTOR_GIP-R_Homo sapiens8243312
27GPCR2601GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Homo sapiens-11326760
28GPCR2602GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Homo sapiens-21326760
29GPCR2598GLUCAGON RECEPTOR_GLUCAGON RECEPTOR_Homo sapiens8144028
30GPCR0977HISTAMINE RECEPTOR_H2_Homo sapiens1703298
31GPCR2447PROSTANOID RECEPTOR_IP_Homo sapiens7512962
32GPCR2408LYSOPHOSPHOLIPID RECEPTOR_LPA4_Homo sapiens12724320
33GPCR0871GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Homo sapiens1516719
34GPCR1158MELANOCORTIN RECEPTOR_MC1_Homo sapiens1516719
35GPCR1181MELANOCORTIN RECEPTOR_MC2_Homo sapiens1325670
36GPCR1188MELANOCORTIN RECEPTOR_MC3_Homo sapiens8463333
37GPCR1195MELANOCORTIN RECEPTOR_MC4_Homo sapiens8392067
38GPCR1206MELANOCORTIN RECEPTOR_MC5_Homo sapiens8185570
39GPCR2502TACHYKININ RECEPTOR_NK1_Homo sapiens1370820
40GPCR2504TACHYKININ RECEPTOR_NK2_Homo sapiens-11370820
41GPCR2509TACHYKININ RECEPTOR_NK2_Homo sapiens-21370820
42GPCR2513TACHYKININ RECEPTOR_NK3_Homo sapiens1370820
43GPCR2381P2Y RECEPTOR_P2Y11_Homo sapiens9405388
44GPCR2621VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Homo sapiens8396727
45GPCR2615PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR_Homo sapiens1658941
46GPCR2610PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE RECEPTOR_Homo sapiens7797535
47GPCR1104LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-512220620
48GPCR1119LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-112220620
49GPCR1120LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-812220620
50GPCR1122LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-612220620
51GPCR1124LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-712220620
52GPCR1126LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-212220620
53GPCR1130LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-312220620
54GPCR1135LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-912220620
55GPCR1137LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-412220620
56GPCR1138LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Homo sapiens-1012220620
57GPCR2617SECRETIN RECEPTOR_SCT-R_Homo sapiens1646711
58GPCR2526TRACE AMINE RECEPTOR_TaR_Homo sapiens-111459929
59GPCR2527TRACE AMINE RECEPTOR_TaR_Homo sapiens-411459929
60GPCR2529TRACE AMINE RECEPTOR_TaR-1_Homo sapiens11459929
61GPCR2539TRACE AMINE RECEPTOR_TaR-3_Homo sapiens11459929
62GPCR2541TRACE AMINE RECEPTOR_TaR-4_Homo sapiens11459929
63GPCR2543TRACE AMINE RECEPTOR_TaR-5_Homo sapiens11459929
64GPCR0886GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Homo sapiens-28552586
65GPCR0887GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Homo sapiens-18552586
66GPCR0889GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Homo sapiens-38552586
67GPCR2567VASOPRESSIN AND OXYTOCIN RECEPTOR_V2_Homo sapiens1534150
68GPCR2627VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Homo sapiens-11675791
69GPCR2630VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Homo sapiens-21675791
70GPCR2634VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC2_Homo sapiens7733904



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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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