gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0435 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE LARG RhoGEF

Cross References:
UniProt Q6P526 EMBL BC063117
InterPro IPR001478 | IPR015212 | IPR015721
PFAM PF00595 | PF09128

Details:
NAME LARG RhoGEF-Homo sapiens-2
DESCRIPTION ARHGEF12 protein .
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ARHGEF12
SEQUENCE 
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTGLVQRCVIIQKDD
NGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIKSGSY
VALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVLMGEENN
VVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQLSKATGS
AQDGAVVTPSRPLGD
 FRAGMENT YES
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 12024019 | 14607242
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:15251227 | 12024019
3GPR0002Galpha-q-Homo sapiens-2
4GPR0237Galpha-q-Homo sapiens-1

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