gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0436 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE LARG RhoGEF

Cross References:
UniProt Q9D7D6 EMBL AK009331
InterPro IPR001478
PFAM PF00595

Details:
NAME LARG RhoGEF-Mus musculus-1
DESCRIPTION Adult male tongue cDNA, RIKEN full-length enriched library,clone:2310014B11 product:hypothetical PDZ domain (also known as DHR orGLGF) containing protein, full insert sequence.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Arhgef12
SEQUENCE 
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSSSHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVKQS
VSWESCGLQRLPRL
 FRAGMENT NO
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 12024019 | 14607242
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gq/11 REFERENCES:15251227 | 12024019
5GPR0240Galpha-q-Mus musculus

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