gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0444 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE PDZ RhoGEF

Cross References:
UniProt Q6PFW2 EMBL BC057394 | AL356104 | AL157713
InterPro IPR000219 | IPR001478 | IPR001849 | IPR011993 | IPR000342 | IPR015212 | IPR015721
GENEID 9826
PFAM PF00595 | PF09128 | PF00621

Details:
NAME PDZ RhoGEF-Homo sapiens-1
DESCRIPTION Rho guanine nucleotide exchange factor (GEF) 11.
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ARHGEF11 | RP11-356J7.2-001
SEQUENCE 
MSVRLPQSIDRLSSLSSLGDSAPERKSPSHHRQPSDASETTGLVQRCVIIQKDQHGFGFT
VSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLL
GSSPSSMGISGLQQDPSPAGAPRITSVIPSPPPPPPLPPPQRITGPKPLQDPEVQKHATQ
ILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGSVDILPLY
GDTSQRPSEGRLSLD
 FRAGMENT NO
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 11799111 | 14607242
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:1525227 | 16182515
3GPR0002Galpha-q-Homo sapiens-2
4GPR0237Galpha-q-Homo sapiens-1

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