gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0448 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE PDZ RhoGEF

Cross References:
UniProt Q3TDN6 EMBL AK170102
InterPro IPR001849 | IPR011993 | IPR015721

Details:
NAME PDZ RhoGEF-Mus musculus-2
DESCRIPTION NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enrichedlibrary, clone:F630017A09 product:Rho guanine nucleotide exchangefactor .
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Arhgef11
SEQUENCE
DLVVLLQRQEEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSE
LGPPQIYELVALTSSDKNIWMELLEEAVQNATKHPGDAPVLNHPSPPGSQEPAYQGSTSS
RVEVNDSEVYPTEREPKKPSEGPGPEQRGQDKQLLAQEGPEQEEDAEELRALPCPPPSLD
GENRGIRTRDPVLLALTGPLLMEGLADAALEDVENLRHLILWCLLPGHTVKTQAAGEPED
DLTPTPSVVSITSHP
FRAGMENT YES
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 11799111 | 14607242
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gq/11 REFERENCES:1525227 | 16182515
5GPR0240Galpha-q-Mus musculus


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