gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0449 ::
FAMILY Guanine nucleotide exchange factors
SUBFAMILY RhoGEFs
TYPE PDZ RhoGEF

Cross References:
UniProt Q3U048 EMBL AK157225
InterPro IPR000219 | IPR001331 | IPR001478 | IPR001849 | IPR011993 | IPR000342 | IPR015212 | IPR015721
PFAM PF00595 | PF09128 | PF00621

Details:
NAME PDZ RhoGEF-Mus musculus-3
DESCRIPTION Activated spleen cDNA, RIKEN full-length enriched library,clone:F830207D02 product:Rho guanine nucleotide exchange factor .
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Arhgef11
SEQUENCE 
MSIRLPHSIDRLSSLSSLGDSTPERTSPSHHRQPSDTSETTGLVQRCVIIQKDQHGFGFT
VSGDRIVLVQSVRPGGAAMRAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLL
GSSPSSIGVSGLQQNPSLSGGPRVNPTIPPPPPPPPLPPPQHITGPKPLQDPEVQKHATQ
ILRNMLRQEEKELQDVLPLCGETSQRTCEGRLSVDSQEADSGLDSGTERFPSISESLVNR
NSVLSDPGLDSPQTS
 FRAGMENT YES
FUNCTION -
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227 | 11799111 | 14607242
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gq/11 REFERENCES:1525227 | 16182515
5GPR0240Galpha-q-Mus musculus

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