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gpDB::Effector View
Entry 1 of 1 :: EFF0528 ::
FAMILY Phospholipases C
SUBFAMILY Phospholipases C beta
TYPE Phospholipase C beta 1

Cross References:
UniProt P10687 EMBL M20636
InterPro IPR000008 | IPR011992 | IPR015359 | IPR013841 | IPR001192 | IPR000909 | IPR001711 | IPR014815
PRODOM PD001202 GENEID 24654
PRINTS PR00390 PFAM PF00168 | PF09279 | PF00388 | PF00387 | PF08703

Details:
NAME Phospholipase C beta-1-Rattus norvegicus
DESCRIPTION 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1(EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Plcb1
SEQUENCE 
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRD
 FRAGMENT NO
FUNCTION The production of the second messenger moleculess diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) iss mediated by activated phosphatidylinositol-specific phospholipases C enzymes
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 16182515 | 11015615
1GPR0032Galpha-11-Rattus norvegicus
2GPR0045Galpha-15-Rattus norvegicus
3GPR0242Galpha-q-Rattus norvegicus
Family:Gbeta REFERENCES:15251227 | 11015615 | 8383116
4GPR0149Gbeta-1-Rattus norvegicus-2
5GPR0157Gbeta-2-Rattus norvegicus-2
6GPR0162Gbeta-3-Rattus norvegicus
7GPR0166Gbeta-4-Rattus norvegicus
8GPR0169Gbeta-5-Rattus norvegicus
9GPR0396Gbeta-2-Rattus norvegicus-1
10GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 11015615 | 8383116
11GPR0190Ggamma-5-Rattus norvegicus
12GPR0194Ggamma-7-Rattus norvegicus
13GPR0197Ggamma-8-Rattus norvegicus
14GPR0201Ggamma-11-Rattus norvegicus
15GPR0256Ggamma-2-Rattus norvegicus
16GPR0257Ggamma-3-Rattus norvegicus
17GPR0258Ggamma-4-Rattus norvegicus
18GPR0259Ggamma-10-Rattus norvegicus
19GPR0260Ggamma-12-Rattus norvegicus

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