gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0693 ::
FAMILY GTPase activating proteins
SUBFAMILY Ras GTPase activating proteins
TYPE Ras GTPase activating protein 2

Cross References:
UniProt Q15283 | O00695 | Q15284 | Q92594 | Q99577 | Q9UEQ2 EMBL D78155 | D78156 | D82880 | D82881 | AF115573
InterPro IPR001562 | IPR000008 | IPR001849 | IPR011993 | IPR001936
GENEID 5922 MIM 601589
PRINTS PR00360 | PR00402 PFAM PF00779 | PF00168 | PF00169 | PF00616

Details:
NAME Ras GTPase activating protein-2-Homo sapiens
DESCRIPTION Ras GTPase-activating protein 2 (GAP1m).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RASA2 | GAP1M | RASGAP
SEQUENCE
MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMR
DCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGK
VAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKAC
HGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQ
FQVEEEDIEKLEIRI
FRAGMENT NO
FUNCTION Inhibitory regulator of the Ras-cyclic AMP pathway
Interacting with G-proteins:
Family:G12/13 REFERENCES:15251227
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens


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