gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0857 ::
FAMILY Tyr protein kinases
SUBFAMILY Tyr protein kinases
TYPE Src tyrosine kinase

Cross References:
UniProt Q76P87 EMBL AL133293 | CH471077
InterPro IPR000719 | IPR000980 | IPR001452 | IPR001245 | IPR008266
PRODOM PD000001 | PD000093 | PD000066
PRINTS PR00401 | PR00452 | PR00109 PFAM PF07714 | PF00017 | PF00018

Details:
NAME Src tyrosine kinase-Homo sapiens-4
DESCRIPTION V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian) (V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian),isoform CRA_d).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE SRC | RP5-823N20.1-005 | hCG_38048
SEQUENCE
MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS
KHADGLCHRLTTVCP
FRAGMENT NO
FUNCTION -
Interacting with G-proteins:
Family:Gi/o REFERENCES:11007482 | 15251227 | 12209124
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
6GPR0020Galpha-o1-Homo sapiens
7GPR0334Galpha-o-Homo sapiens
Family:Gs REFERENCES:11007482 | 15251227 | 12209124
8GPR0119Galpha-s-Homo sapiens-2
9GPR0263Galpha-s-Homo sapiens-4
10GPR0266Galpha-s-Homo sapiens-5
11GPR0267Galpha-s-Homo sapiens-6
12GPR0277Galpha-s-Homo sapiens-7
13GPR0278Galpha-s-Homo sapiens
14GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory