gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1007 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY LPA1

Cross References:
UniProt Q92633 | O00656 | O00722 | P78351 EMBL U80811 | Y09479 | Y09479 | U78192 | AY322546 | BC030615 | BC036034
InterPro IPR002277 | IPR000276 | IPR004065 GPCRDB EDG2_HUMAN
GENEID 1902 MIM 602282
PRINTS PR01148 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_LPA1_Homo sapiens
DESCRIPTION Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG2 | LPA1
SEQUENCE 
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:9600933
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:9070858
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:9600933
10GPR0002Galpha-q-Homo sapiens-2
11GPR0029Galpha-11-Homo sapiens
12GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory