gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1008 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY LPA1

Cross References:
UniProt Q28031 EMBL U48236
InterPro IPR002277 | IPR000276 | IPR004065 GPCRDB EDG2_BOVIN
GENEID 281136
PRINTS PR01148 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_LPA1_Bos taurus
DESCRIPTION Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1)(Rec1.3).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE EDG2 | LPA1
SEQUENCE
MAAAFTSSPVVSQPQFTAMNEQQCFSNESIAFFYNRSGKYLATEWNTVTKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTVSVANLLAIAIERHITVFRMQLHARMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENTSGPTEGSDRSASSLNHTILAGVHSND
HSVV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9070858
1GPR0017Galpha-o1-Bos taurus
2GPR0219Galpha-i1-Bos taurus
3GPR0294Galpha-i2-Bos taurus-2
4GPR0295Galpha-i2-Bos taurus-1
Family:Gq/11 REFERENCES:9600933
5GPR0027Galpha-11-Bos taurus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory