gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::G-protein View
Entry 1 of 1 :: GPR0017 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-o
TYPE Galpha-o1

Cross References:
UniProt P08239 | A5PJS0 EMBL M16116 | X12924 | BC142217 | M14489
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 281792
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-o1-Bos taurus
DESCRIPTION Guanine nucleotide-binding protein G(o) subunit alpha (GTP-bindingprotein G39).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
POST TRANSLATION MODIFICATIONS null GENE GNAO1
SEQUENCE 
MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SPELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGSNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0001Adenylate cyclase-1-Bos taurusInhibition15251227 | 15922020 | 14993377 | 11376933
2EFF0947Tubulin-Bos taurus-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
3EFF0948Tubulin-Bos taurus-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
4EFF0949Tubulin-Bos taurus-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
5EFF0950Tubulin-Bos taurus-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
6EFF0951Tubulin-Bos taurus-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
7EFF0952Tubulin-Bos taurus-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
8EFF0953Tubulin-Bos taurus-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
9EFF1441Voltage dependent N type calcium channel-Bos taurusInhibition15251227 | 11031246
10EFF1467Voltage dependent P/Q type calcium channel-Bos taurus-1Inhibition15251227 | 11031246 | 11395521
11EFF1468Voltage dependent P/Q type calcium channel-Bos taurus-2Inhibition15251227 | 11031246 | 11395521
12EFF1497Voltage dependent R type calcium channel-Bos taurusInhibition15251227 | 11031246

Coupling with GPCRs:
1GPCR0172ADENOSINE RECEPTOR_A1_Bos taurus1662665
2GPCR0235ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Bos taurus8662784
3GPCR0257ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Bos taurus2164221
4GPCR0416ANGIOTENSIN RECEPTOR_AT1_Bos taurus1310139
5GPCR0441ANGIOTENSIN RECEPTOR_AT2_Bos taurus8663053
6GPCR0397ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Bos taurus9363896
7GPCR2637EXTRACELLULAR CALCIUM-SENSING RECEPTOR_CASR_Bos taurus11152759
8GPCR0551CB1_CB2_Bos taurus7689702
9GPCR0558CHEMOKINE RECEPTOR (CC)_CCR11_Bos taurus10734104
10GPCR0632CHEMOKINE RECEPTOR (CX3C)_CXCR2_Bos taurus1891716
11GPCR0641CHEMOKINE RECEPTOR (CX3C)_CXCR4_Bos taurus8629022
12GPCR0780DOPAMINE RECEPTOR_D2_Bos taurus2974511
13GPCR2418PROSTANOID RECEPTOR_DP2_Bos taurus12721327
14GPCR2429PROSTANOID RECEPTOR_EP3_Bos taurus11095474
15GPCR0819ENDOTHELIN RECEPTOR_ET-B_Bos taurus1848367
16GPCR0855GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Bos taurus9139796
17GPCR1008LYSOPHOSPHOLIPID RECEPTOR_LPA1_Bos taurus9070858
18GPCR0868GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Bos taurus-21516719
19GPCR0128ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M2_Bos taurus3443095
20GPCR0152ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M4_Bos taurus3037705
21GPCR1220MELATONIN RECEPTOR_MT1_Bos taurus7946354
22GPCR1901OPIOID AND OPIOID-LIKE RECEPTOR_MU OPIOID PEPTIDE (MOR)_Bos taurus8393525
23GPCR2558VASOPRESSIN AND OXYTOCIN RECEPTOR_OT_Bos taurus1313946
24GPCR2477SOMATOSTATIN RECEPTOR_SST2_Bos taurus7622071
25GPCR0896GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Bos taurus-18552586
26GPCR1257NEUROPEPTIDE Y RECEPTOR_Y2_Bos taurus7559383



Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory