gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1013 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY LPA2

Cross References:
UniProt Q9HBW0 | O00543 | O43431 EMBL AF011466 | AF233092 | AF197929 | AY322548 | AC002306 | BC025695
InterPro IPR004066 | IPR000276 | IPR004065 GPCRDB EDG4_HUMAN
GENEID 9170 MIM 605110
PRINTS PR01528 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_LPA2_Homo sapiens
DESCRIPTION Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG4 | LPA2
SEQUENCE 
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:12215548
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:9525886
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:9525886
10GPR0002Galpha-q-Homo sapiens-2
11GPR0029Galpha-11-Homo sapiens
12GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory