gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1090 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P2

Cross References:
UniProt O95136 | Q86UN8 EMBL AF034780 | AY262688 | BC069598
InterPro IPR004063 | IPR000276 | IPR004061 PDB 1ZTI GPCRDB EDG5_HUMAN
GENEID 9294 MIM 605111
PRINTS PR01525 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P2_Homo sapiens
DESCRIPTION Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5)(Endothelial differentiation G-protein coupled receptor 5)(Sphingosine 1-phosphate receptor 2) (S1P2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG5
SEQUENCE 
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10488065
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:10488065
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:10617617
10GPR0002Galpha-q-Homo sapiens-2
11GPR0029Galpha-11-Homo sapiens
12GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory