gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1097 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P3

Cross References:
UniProt Q99500 | Q7Z5I2 EMBL X83864 | AF022139 | AY322540 | BC060827 | BC069579
InterPro IPR000987 | IPR004062 | IPR000276 | IPR004061 GPCRDB EDG3_HUMAN
GENEID 1903 MIM 601965
PRINTS PR01524 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P3_Homo sapiens
DESCRIPTION Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3)(Endothelial differentiation G-protein coupled receptor 3)(Sphingosine 1-phosphate receptor 3) (S1P3).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG3
SEQUENCE
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10488065
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:9409733
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:9409733
10GPR0002Galpha-q-Homo sapiens-2
11GPR0029Galpha-11-Homo sapiens
12GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory