gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1100 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P5

Cross References:
UniProt Q9H228 | Q6NW11 EMBL AF331840 | AK074661 | AF317676 | AY262689 | AB083602 | AC011461 | BC034703 | BC067781
InterPro IPR005386 | IPR000276 | IPR004061 GPCRDB EDG8_HUMAN
GENEID 53637 MIM 605146
PRINTS PR01561 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P5_Homo sapiens
DESCRIPTION Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiationsphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphatereceptor 5) (S1P5).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDG8
SEQUENCE 
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10799507
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:10799507
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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