gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1101 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P5

Cross References:
UniProt Q9JKM5 | Q9QY79 EMBL AF115249 | AF233649
InterPro IPR005386 | IPR000276 | IPR004061 GPCRDB EDG8_RAT
GENEID 60399
PRINTS PR01561 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P5_Rattus norvegicus
DESCRIPTION Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiationsphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphatereceptor 5) (S1P5) (Nerve growth factor-regulated G-protein-coupledreceptor 1) (NRG-1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Edg8 | Nrg1
SEQUENCE
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALA
ASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLE
ACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSR
SRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANS
LLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLD
RSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10799507
1GPR0036Galpha-12-Rattus norvegicus
Family:Gi/o REFERENCES:10799507
2GPR0026Galpha-o-Rattus norvegicus
3GPR0111Galpha-i3-Rattus norvegicus
4GPR0221Galpha-i1-Rattus norvegicus
5GPR0229Galpha-i2-Rattus norvegicus


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