gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1102 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P5

Cross References:
UniProt Q91X56 | Q99MN8 EMBL BC012232 | AF327535 | AK081126
InterPro IPR005386 | IPR000276 | IPR004061 GPCRDB EDG8_MOUSE
GENEID 94226
PRINTS PR01561 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P5_Mus musculus
DESCRIPTION Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiationsphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphatereceptor 5) (S1P5) (Lysophospholipid receptor B4).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Edg8 | Lpb4
SEQUENCE 
MEPGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLV
LVRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALA
ASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGASLLLGLLPALGWNCLGRLE
TCSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSR
SRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANS
LLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAAGPSGGGLRRCLPPTLD
RSSSPSEHLSPQQDGVDTSCSTGSPGVATANRSLVPTATD
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10799507
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:10799507
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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