gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1195 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY MELANOCORTIN RECEPTOR
SUBFAMILY MC4

Cross References:
UniProt P32245 | Q16317 | Q3MIJ6 EMBL L08603 | S77415 | AY236539 | BC069172 | BC101802 | BC111992
InterPro IPR000276 | IPR000155 | IPR001908 | IPR001671 PDB 2IQP | 2IQR | 2IQS | 2IQU | 2IQV | 2IQW GPCRDB MC4R_HUMAN
GENEID 4160 MIM 155541 | 601665
PRINTS PR00237 | PR00534 | PR00535 | PR01062 PFAM PF00001

Details:
NAME MELANOCORTIN RECEPTOR_MC4_Homo sapiens
DESCRIPTION Melanocortin receptor 4 (MC4-R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE MC4R
SEQUENCE
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8392067
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory