gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0120 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ACETYLCHOLINE RECEPTOR (MUSCARINIC)
SUBFAMILY M1

Cross References:
UniProt P11229 EMBL X52068 | X15263 | Y00508 | AF498915 | BC007740 | BC022984
InterPro IPR000276 | IPR002228 | IPR000995 GPCRDB ACM1_HUMAN
GENEID 1128 MIM 118510
PRINTS PR00237 | PR00243 | PR00538 PFAM PF00001

Details:
NAME ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M1_Homo sapiens-2
DESCRIPTION Muscarinic acetylcholine receptor M1.
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CHRM1
SEQUENCE 
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10821841
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:3037705
3GPR0002Galpha-q-Homo sapiens-2
4GPR0029Galpha-11-Homo sapiens
5GPR0237Galpha-q-Homo sapiens-1

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 Dept. of Cell Biology and Biophysics
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