| Details: |
| NAME |
ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M2_Rattus norvegicus |
| DESCRIPTION |
Muscarinic acetylcholine receptor M2. |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Chrm2 | Chrm-2 |
| SEQUENCE |
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimers with Muscarinic M3 Receptors. Heterodimerization results in altered internalization of the receptors
|
METHOD |
Chimeric receptor reconstitution studies
|
REFERENCES |
10490911
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 3443095 | | 1 | GPR0026 | Galpha-o-Rattus norvegicus | | 2 | GPR0111 | Galpha-i3-Rattus norvegicus | | 3 | GPR0221 | Galpha-i1-Rattus norvegicus | | 4 | GPR0229 | Galpha-i2-Rattus norvegicus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
