gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1251 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NEUROPEPTIDE Y RECEPTOR
SUBFAMILY Y1

Cross References:
UniProt O02813 EMBL AF005778
InterPro IPR000276 | IPR000351 | IPR000611 GPCRDB NPY1R_CANFA
GENEID 399518
PRINTS PR00237 | PR01013 | PR01012 PFAM PF00001

Details:
NAME NEUROPEPTIDE Y RECEPTOR_Y1_Canis familiaris
DESCRIPTION Neuropeptide Y receptor type 1 (NPY1-R).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE NPY1R
SEQUENCE
MNSTSFSQVENHSIFCNFSENSQFLAFESDDCHLPLAMIFTLALAYGAVIILGVTGNLAL
IMIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQC
VSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVVSSLPFLIYQVLTD
EPFQNVTLDAFKDKYVCFDKFPSDSHRLSYTTLLLMLQYFGPLCFIFICYFKIYIRLKRR
NNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLL
FLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSK
TSLKQASPVAFKKINNDDNEKI
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12524448

Coupling with G-proteins:
Family:Gi/o REFERENCES:1321422
1GPR0223Galpha-i2-Canis familiaris
Family:Gq/11 REFERENCES:1321422
2GPR0233Galpha-q-Canis familiaris


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory