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gpDB::G-protein View
Entry 1 of 1 :: GPR0233 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-q
TYPE Galpha-q

Cross References:
UniProt Q28294 EMBL L76257
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-q-Canis familiaris
DESCRIPTION Guanine nucleotide-binding protein G(q) subunit alpha (Guaninenucleotide-binding protein alpha-q).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
POST TRANSLATION MODIFICATIONS null GENE GNAQ
SEQUENCE 
MACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSG
YSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFEN
PYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPT
TGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN
RMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAR
EFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0288Caveolin-1-Canis familiarisGq Binds Caveolin to Concentrate in Caveolae16182515 | 11251080
2EFF1010Tubulin-Canis familiaris-1Potentiates receptor-induced PLC-beta activation16182515
3EFF1011Tubulin-Canis familiaris-2Potentiates receptor-induced PLC-beta activation16182515

Coupling with GPCRs:
1GPCR00695-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2A_Canis familiaris1765383
2GPCR0201ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1A(Adrenoceptor)_Canis familiaris8396931
3GPCR0218ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1B(Adrenoceptor)_Canis familiaris1662393
4GPCR0424ANGIOTENSIN RECEPTOR_AT1_Canis familiaris-28865167
5GPCR0427ANGIOTENSIN RECEPTOR_AT1_Canis familiaris-18865167
6GPCR0472BRADYKININ RECEPTOR_B2_Canis familiaris1657928
7GPCR0741CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK2_Canis familiaris1280419
8GPCR0821ENDOTHELIN RECEPTOR_ET-B_Canis familiaris1848367
9GPCR0899GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH1_Canis familiaris1333190
10GPCR0875GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Canis familiaris1516719
11GPCR2367OREXIN RECEPTOR_Orexin 2_Canis familiaris9491897
12GPCR0880GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Canis familiaris8552586
13GPCR1251NEUROPEPTIDE Y RECEPTOR_Y1_Canis familiaris1321422



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