| Details: |
| NAME |
ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M3_Homo sapiens-1 |
| DESCRIPTION |
Muscarinic acetylcholine receptor M3. |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
CHRM3 |
| SEQUENCE |
MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10383466
|
| HETERODIMER INFORMATION |
Forms heterodimers with Muscarinic M2 Receptors. Heterodimerization results in altered internalization of the receptors
|
METHOD |
Chimeric receptor reconstitution studies
|
REFERENCES |
10490911
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
