| Details: |
| NAME |
ADENOSINE RECEPTOR_A2A_Rattus norvegicus-1 |
| DESCRIPTION |
Adenosine receptor A2a. |
| SPECIES |
Rattus norvegicus |
COMMON NAME |
Rat |
NCBI Taxonomy |
10116 |
| GENE |
Adora2a |
| SEQUENCE |
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12804599
|
| HETERODIMER INFORMATION |
Forms heterodimers with Dopamine D2. Heterodimerization results in co-desensitization and co-internalization of the receptors
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11872740
|
| HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptors 5. Dimerization results in enhanced ERK activity
|
METHOD |
Immunoprecipitation
|
REFERENCES |
12189203
|
| Coupling with G-proteins: |
| Family:Gs |
REFERENCES: | 1662665 | | 1 | GPR0124 | Galpha-s-Rattus norvegicus-2 | | 2 | GPR0392 | Galpha-s-Rattus norvegicus-1 |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
