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gpDB::G-protein View
Entry 1 of 1 :: GPR0124 ::
CLASS Galpha
FAMILY Gs
SUBFAMILY Galpha-s
TYPE Galpha-s

Cross References:
UniProt P63095 | P04894 | P08755 | Q05087 | Q45QM7 | Q9Z1R8 EMBL M12673 | M17525 | L10326 | AF107844 | DQ120475 | DQ120476 | BC061967
InterPro IPR001019 | IPR000367 | IPR011025
PRODOM PD000281
GENEID 24896
PRINTS PR00318 | PR00443 PFAM PF00503

Details:
NAME Galpha-s-Rattus norvegicus-2
DESCRIPTION Guanine nucleotide-binding protein G(s) subunit alpha isoforms short(Adenylate cyclase-stimulating G alpha protein) (G-alpha-8).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
POST TRANSLATION MODIFICATIONS null GENE Gnas | Gnas1
SEQUENCE 
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA
NPENQFRVDYILSVMNVPNFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK
VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY
PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0011Adenylate cyclase-2-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
2EFF0019Adenylate cyclase-3-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
3EFF0026Adenylate cyclase-4-Rattus norvegicus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
4EFF0027Adenylate cyclase-4-Rattus norvegicus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
5EFF0036Adenylate cyclase-5-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
6EFF0042Adenylate cyclase-6-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
7EFF0052Adenylate cyclase-7-Rattus norvegicus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
8EFF0053Adenylate cyclase-7-Rattus norvegicus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
9EFF0059Adenylate cyclase-8-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
10EFF0867Src tyrosine kinase-Rattus norvegicus-1Stimulation11007482 | 15251227 | 12209124
11EFF0868Src tyrosine kinase-Rattus norvegicus-2Stimulation11007482 | 15251227 | 12209124
12EFF0870Src tyrosine kinase-Rattus norvegicus-3Stimulation11007482 | 15251227 | 12209124
13EFF1336Tubulin-Rattus norvegicus-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
14EFF1337Tubulin-Rattus norvegicus-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
15EFF1338Tubulin-Rattus norvegicus-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
16EFF1339Tubulin-Rattus norvegicus-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
17EFF1340Tubulin-Rattus norvegicus-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
18EFF1342Tubulin-Rattus norvegicus-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
19EFF1343Tubulin-Rattus norvegicus-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
20EFF1344Tubulin-Rattus norvegicus-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
21EFF1345Tubulin-Rattus norvegicus-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
22EFF1346Tubulin-Rattus norvegicus-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
23EFF1347Tubulin-Rattus norvegicus-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
24EFF1348Tubulin-Rattus norvegicus-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR00885-HYDROXYTRYPTAMINE RECEPTOR_5-HT-4_Rattus norvegicus2849052
2GPCR00985-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Rattus norvegicus-18522988
3GPCR00995-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Rattus norvegicus-28522988
4GPCR01065-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Rattus norvegicus-18397408
5GPCR01105-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Rattus norvegicus-28397408
6GPCR0179ADENOSINE RECEPTOR_A2A_Rattus norvegicus-31662665
7GPCR0181ADENOSINE RECEPTOR_A2A_Rattus norvegicus-21662665
8GPCR0183ADENOSINE RECEPTOR_A2A_Rattus norvegicus-11662665
9GPCR0236ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Rattus norvegicus8662784
10GPCR0188ADENOSINE RECEPTOR_A2B_Rattus norvegicus11048721
11GPCR2573CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_ADRENOMEDULIN RECEPTOR_Rattus norvegicus8549809
12GPCR0307ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Rattus norvegicus2825170
13GPCR0324ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Rattus norvegicus-33041227
14GPCR0338ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Rattus norvegicus-13041227
15GPCR0369ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Rattus norvegicus-23041227
16GPCR0399ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Rattus norvegicus2570461
17GPCR2578CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Rattus norvegicus1331173
18GPCR0735CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Rattus norvegicus8503909
19GPCR2582CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Rattus norvegicus2542467
20GPCR2588CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Rattus norvegicus1280419
21GPCR2590CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Rattus norvegicus8536644
22GPCR0758DOPAMINE RECEPTOR_D1_Rattus norvegicus2144334
23GPCR0809DOPAMINE RECEPTOR_D5_Rattus norvegicus1831904
24GPCR2423PROSTANOID RECEPTOR_EP2_Rattus norvegicus7910583
25GPCR2427PROSTANOID RECEPTOR_EP3_Rattus norvegicus11095474
26GPCR2438PROSTANOID RECEPTOR_EP4_Rattus norvegicus8016385
27GPCR0817ENDOTHELIN RECEPTOR_ET-A_Rattus norvegicus1849646
28GPCR0843GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Rattus norvegicus9139796
29GPCR2594GASTRIC INHIBITORY POLYPEPTIDE (GIP) RECEPTOR_GIP-R_Rattus norvegicus8243312
30GPCR2599GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Rattus norvegicus-21326760
31GPCR2603GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Rattus norvegicus-11326760
32GPCR2597GLUCAGON RECEPTOR_GLUCAGON RECEPTOR_Rattus norvegicus8144028
33GPCR0970HISTAMINE RECEPTOR_H2_Rattus norvegicus1703298
34GPCR2446PROSTANOID RECEPTOR_IP_Rattus norvegicus7512962
35GPCR0865GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Rattus norvegicus1516719
36GPCR1192MELANOCORTIN RECEPTOR_MC3_Rattus norvegicus8463333
37GPCR1196MELANOCORTIN RECEPTOR_MC4_Rattus norvegicus8392067
38GPCR1202MELANOCORTIN RECEPTOR_MC5_Rattus norvegicus8185570
39GPCR2498TACHYKININ RECEPTOR_NK1_Rattus norvegicus1370820
40GPCR2511TACHYKININ RECEPTOR_NK2_Rattus norvegicus1370820
41GPCR2514TACHYKININ RECEPTOR_NK3_Rattus norvegicus1370820
42GPCR2620VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Rattus norvegicus8396727
43GPCR2611PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR_Rattus norvegicus1658941
44GPCR2609PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE RECEPTOR_Rattus norvegicus7797535
45GPCR1125LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Rattus norvegicus-212220620
46GPCR1132LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Rattus norvegicus-312220620
47GPCR1139LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Rattus norvegicus-112220620
48GPCR2618SECRETIN RECEPTOR_SCT-R_Rattus norvegicus1646711
49GPCR2528TRACE AMINE RECEPTOR_TaR-1_Rattus norvegicus11459929
50GPCR2532TRACE AMINE RECEPTOR_TaR-10_Rattus norvegicus11459929
51GPCR2533TRACE AMINE RECEPTOR_TaR-11_Rattus norvegicus11459929
52GPCR2534TRACE AMINE RECEPTOR_TaR-12_Rattus norvegicus11459929
53GPCR2536TRACE AMINE RECEPTOR_TaR-14_Rattus norvegicus11459929
54GPCR2537TRACE AMINE RECEPTOR_TaR-15_Rattus norvegicus11459929
55GPCR2538TRACE AMINE RECEPTOR_TaR-2_Rattus norvegicus11459929
56GPCR2540TRACE AMINE RECEPTOR_TaR-3_Rattus norvegicus11459929
57GPCR2542TRACE AMINE RECEPTOR_TaR-4_Rattus norvegicus11459929
58GPCR2544TRACE AMINE RECEPTOR_TaR-6_Rattus norvegicus11459929
59GPCR2545TRACE AMINE RECEPTOR_TaR-7_Rattus norvegicus11459929
60GPCR2546TRACE AMINE RECEPTOR_TaR-9_Rattus norvegicus-111459929
61GPCR2547TRACE AMINE RECEPTOR_TaR-9_Rattus norvegicus-211459929
62GPCR0881GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Rattus norvegicus8552586
63GPCR2568VASOPRESSIN AND OXYTOCIN RECEPTOR_V2_Rattus norvegicus1534150
64GPCR2626VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Rattus norvegicus-11675791
65GPCR2632VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Rattus norvegicus-21675791
66GPCR2633VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC2_Rattus norvegicus7733904



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